BIO-CHIP Pandemic Phone Peripheral

Pandemics such as the recent SARS COVID-19 outbreak need quicker more accurate testing that is inexpensive and can be quickly mass produced.  

This can be achieved through Bio-sensors. Specifically CRISPR immobilized on a graphene field-effect transistor.  These "CRISPR chips" can be mass produced and fitted with printed DNA.  This can be done after a virus is identified and the genetic sequence is published online as in the COVID-19 pandemic. Once the DNA/RNA is printed it is sent to be complexed with the mass produced "CRIPSR chips".  

These are then made into a smartphone peripheral.  The peripheral is sent with a nasal swab kit to every home. The test can easily be self administered and reported to a national database via smartphone, and should only take minutes.  Scaling this solution globally would stop a worldwide pandemic in its tracks, or at least contain it mainly to its country of origin.

This solution will solve the problem of how to detect cases during any future pandemic. This test would have to be given to hundreds of millions if not billions of people during a worldwide pandemic and must be mass produced quickly.  

Current tests including the PCR/RT-PCR which has been very slowly ramped up to combat the SARS COVID-19 pandemic is inherently slow and laborious. It is hard to quickly mass produce and difficult for the general populace to self test and report.  "CRIPSR-CHIP" diagnostics which can be performed at home by each family and which will be self reported over the internet will solve most of the problems associated with the current testing methodology. It will bring about fast, standardized, mass produced at home testing which will stop the majority of damage from any future pandemic before it becomes too extreme.  

Through new DNA printing technology and the ability to quickly mass produce "CRISPR chips" with available, but augmented, microchip manufacturing, this can be quickly and efficiently done.  CRISPR graphene transistors complexed with printed viral DNA/RNA will test a sample from a nasal swab in minutes, and connected to a smartphone will immediately report the result.  

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556128/pdf/nihms-1023243.pdf

My solution uses CRISPR chip technology to test for the DNA or RNA of a virus and smartphones to collect this data and send it to health agencies.  

Graphene field effect transistors have a much greater voltage sensitivity than conventional transistors.  With this greater sensitivity they can easily detect the voltage changes caused by biochemical surface reactions such as the binding of DNA or RNA to CRISPR or the binding of DNA to DNA probes.

DNA printing.  DNA can now be quickly and cheaply printed in mass quantities on silicon wafers.  

CRISPR CHIP.  Combines the Graphene field effect transistors with chemical modifications that allow for the attachment of CRISPR cas systems which target specific DNA or RNA sequences with high specificity.  

SMART PHONE PERIPHERAL.  Making the CRISPR chips compatible with usb-c output will enable the results to be read on any smartphone.

WEB SERVICE. Web services can automatically collect the data uploaded to smartphones.  

conformation of proper swabbing technique can be done via telemedicine , the person would log on before doing the test themselves so can be monitored.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556128/pdf/nihms-1023243.pdf

This test should be deployed not just countrywide but world wide, the chip precursors can be stock piled until the next epidemic, once viral DNA is sequenced the chips can be complexed with viral guide RNA.  once completed and turned into smart phone peripherals they can be sent to every family in this country, and hopefully every family around the world.  

this work should be under taken by DARPA, our government, CDC, NIH, foundations and other countries governments as well.

it should serve to mitigate most of the damage from any future pandemic for each and every country if employed properly.

testing during a world wide viral pandemic is crucial.  This testing must be done countrywide here in the US or hopefully worldwide.  Being able to distribute a CRISPR chip smartphone peripheral to every family during the initial stages of an epidemic is essential. Almost every family in this country has access to a smartphone.  The majority of people around the world do have access to a smart phone and some type of internet now.

These crispr chips can be manufactured in the US and other wealthy nations.  They can be stockpiled in these areas and distribute to poorer nations.