Pre-Vector

Currently, vector-borne diseases account for more than 700,000 deaths per year and are 17% of all infectious diseases in the world, 3. 9 billion people are threatened with dengue fever, with global warming, the periods and zones of these diseases will be prolonged.

Pre-Vector is a platform with a portable, economical and highly efficient diagnostic unit, with a universal interface that does not need to speak a language or have any training, along with a digital platform that gathers all the diagnostic data from the units, stores it in the cloud and analyzes the data to be able to visualize the evolution of these diseases, as well as predict possible development scenarios. 

With this information, the user can make immediate health care decisions and the authorities or organizations can take action to protect health, avoiding human losses and controlling pandemics.

According to the department of virology of the UNAM, in Mexico, in the last 14 years, vector-borne diseases have increased in 30 states of the republic, it is estimated that 60% of the Mexican territory, where more than 50 million people live, present conditions and problems of VBDs, worldwide according to WHO, these diseases cause more than 700,000 deaths annually, more than 3900 million people, in more than 128 countries, are at risk of contracting dengue, with an estimated 96 million cases per year; Malaria causes more than 400,000 deaths worldwide each year, most of them among children under five years of age; the problem could increase because, as pointed out by reports from NASA, the Intergovernmental Panel on Climate Change (IPCC), the World Economic Forum and the WHO itself, climate changes due to global warming will prolong the transmission seasons of VBDs and expand their geographical distribution.

The problem with the VDBs is the little immediate attention that is given, the people without conscience let go, which causes the disease to be transmitted to more people. When the authorities try´s to protect the area, the evolution already threatens with alternate zones. This is the issue that Pre-Vector solves.

Pre-Vector is a platform that integrates IoT concepts, Big Data handling together with state-of-the-art technology in a diagnostic device with operation similar to current glycometers, designed to help a small community, water, dust and fall resistant, self-sustainable energy (without batteries or electrical outlet), portable and with an interface that avoids having to speak a specific language or have some training to perform self-diagnosis and communicate the result to the user, with its high efficiency and low consumption components, The device communicates with a digital system in the cloud that records, stores and analyzes the diagnosis made using a GPS system, achieving real-time display of the evolution of the disease by geographical area and through online variables such as climate, current temperature or even traffic, can predict the possible risk that exists from adjacent areas to contract the disease using statistical and probabilistic analysis, so the user, authorities, organizations or the community itself can make decisions of great value to health.

The areas with the highest incidence and death rate are the least developed, where the tendency to favor the climate for VBDs is greater. With this in mind, Pre-Vector is developed to serve this sector, adapting to weather conditions, with a universal interface and offering access to specialized diagnostic medical infrastructure to the farthest places from the cities, along with an automatic system for the notice of the authorities (digital platform in the cloud) thus offering an essential health service, with field tests it has been validated that the priority needs of this sector are met, taking into account tthe most vulnerable sector (children) to be attended with priority, thus having a diagnostic unit per community,

Currently, the problem of pandemics and diagnosis is global, Pre-Vector is a platform that makes all these problems easier to manage, by giving everyone the opportunity to access the medical diagnostic infrastructure and have the ability to have a real time register in addition to the capacity to predict the evolution of a health emergency, which the platform has, all of this focused on reaching the most vulnerable people due to any type of pandemic and disease, undeveloped areas, all this using the latest technology tools and social responsibility approach that we must have as a younger generation.

Pre-Vector is composed of a state-of-the-art device, which integrates parts of existing technology without a utility model similar to the one used and new technology proven to concept the new global problems, the diagnostic device offers the possibility to perform on-site testing for different diseases, instead of the traditional methods of going to a specific site to perform tests or waiting for the arrival of medical agent for the collection of samples, and then wait for results, the diagnostic device not only solves the barrier of the location, but also with the knowledge (language and training) and power supply (manual dynamo) as well as the efficient and real time capture of diagnostic data (on-site diagnosis), with all this in addition the digital system of collection, storage and analysis of data, is unlike any existing, since, in addition to providing the most updated statistics, offers the visualization on the evolution of different diseases and predicting how the disease will develop, all in real time, features that no other platform offers. 

Including the competition (being only centers and organizations for the diagnosis of infectious diseases) could be interested in the acquisition of the platform, to give it a useful model that could expand its catalog of services, but technologically there is no one who manages the registration and control of the evolution of diseases, as Pre-Vector would.

The integrated technology for the development of the diagnostic unit is the concept of the operation of glucose readers, with a digital test strip reader, a brain for the interpretation of the diagnostic result, a low power consumption display for the interaction between the unit and the user, a high efficiency handheld dynamo for power generation, a battery for energy storage, reengineering by shrinkage to achieve certification against falls, water and dust, development of the software for the universal interface to avoid language problems between the user communication with the diagnostic unit, development of materials that meet the mechanical needs of the device, low power communication by GPS concept for global data capture (even in the most remote areas) and two buttons.

The digital system of data capture and analysis, achieves through matrices, statistical tests and efficient management of information, give the theoretical evolution of the diagnosed diseases, using high efficiency servers and software development to meet a real-time display of all data provided by the diagnostic units.

The technology used in the diagnostic unit is similar to that of current glucose readers, which with a color sensor in conjunction with test strips, react by analyzing the spectrum developed on the test strip so that the unit can diagnose a disease, the batteries are rechargeable (integrated within the system) and the way of feeding is through a manual dynamo which is a mechanical system that generates kinetic mechanical energy in electrical energy (concept of the van de graaff generator) also nowadays there are different processes and certifications to check that a system is "resistant" to different conditions, using specific gaskets for the housing, with all this the communication method (LPWAN concept) is based on a GPS chip as the one used by the cars for the communication on the location data and diagnostic results.

The digital system that collects and analyzes the data will work through a computer server which has the ability to handle the raw data and provide different methods of statistical analysis that can work similar to the operation of WolframAlpha the map that displays the infected areas, the development and possible evolution of diseases, is worked on the google maps API, which currently offers the greatest geographical coverage.

The current problem about vector-borne diseases is the misinformation that exists, on the part of the sick and the health entities, on the part of the sick people, because they do not have medical training or access to health infrastructure, people cannot; first, take immediate action on medical treatment to attend to their disease; second, isolate the person so that they do not transmit the disease with the people around them; Thirdly, informing health authorities about their situation; fourthly, diagnostic methods involve not only transport, but exorbitant payment for anyone who normally lives far from cities, all of which encourages the accelerated evolution of vector-borne diseases, only by those people who are not informed about their medical condition. Health entities (government, organizations, society...) cannot make decisions of great value for the quality of life of people: first, since they do not have information about the possible site of infection that could spread, they cannot make decisions of popular isolation; second, they cannot offer immediate specialized medical care, which is impossible if the disease and the number of people affected are not known; third, they do not have real control of pandemics since they do not have the necessary geographical information about the evolution of the disease. 

Pre-Vector solves all this, the access to specialized and economic medical infrastructure, which also diagnoses on site, communicating remotely with the digital platform that informs the entities in real time about the necessary statistics for decision making, which also analyzes and predicts the possible danger that exists if it is not attended. Breaking the barrier of geography, communication, language and energy all on the same platform. Still, neither the device nor the platform is limited to vector-borne diseases. While the approach could have the greatest impact on these health care issues, the platform can be used for virtually any disease diagnosis for which test strips are available, thus providing the best platform for pandemic capture, analysis and control, at the state, national and global levels.

The impact is variable, we are currently in the phase of integrating the industrial product, however thanks to field tests, it is known that a diagnostic device in a small community can help to make life decisions, up to 30% of a poorly developed marginalized population with a group of 500 inhabitants, cellular production is intended (in a conservative environment) for the sale of 300 units monthly, thus achieving annually the production of 3,600 units that could have an impact (considering the reports on the expansion of diseases and death rate) to save up to 140,000 people in the first year and scalable to reduce up to 95% of deaths due to misinformation (misdiagnosis or not having received medical attention). The theoretical studied impact to be achieved in the next 5 years is to save (annually added) up to 1,000,000 people. Considering that the production variables (300 units per month), with the current statistics (which are increasing) and that the platform is only used for exclusively vector-borne diseases (can be adjusted for the diagnosis of practically any disease with test strips)

In 5 years the goals we have for the development of Pre-Vector are:

1: the setting up of an automated pilot plant with a production of up to 1000 units per month.

2: the development of test strips with international standards for the diagnosis of diseases.

3: the international governmental distribution of the platform.

4: To have reduced by 50% the problems caused by the lack of medical and communication infrastructure.

5: comply with the sustainable business model to meet the goals.

6: Partner with companies and organizations of technology and human development for the implementation of different projects

The current barriers for the development of Pre-Vector is the lack of capital for the completion of the integration of the industrial product, the setting up of the pilot plant and everything related to international certifications and marketing development.
The lack of relations both governmental and private organizations for the sale, distribution and installation of the platform.

Obtaining subsidies from government and private institutions, making a possible pre-sale of diagnostic units, raising funds through prizes for health development and taking advantage of the strategic alliances that come with these prizes and finally the integration of partners for a percentage of profit for large-scale distribution of the physical product.

Currently we integrate the work model among 9 people, but this is due to the country's economic and health situation, the original team included 15 people.

We integrate a work team that has specialists with more than 10 years in the industry in smart city jobs, circular business models and technology development that exploits the concepts of IoT and Big Data, as well as young entrepreneurs who have the value to dedicate their lives to the comprehensive management of the solution. United in the interest of problem solving through technology and responsibility.

We are currently having preliminary contracts with the government of Puebla, Mexico, but due to the lack of internal and external investment and the disappearance of national institutions for funding technology and science within the country, we do not yet have a response from any strategic alliance

The business model on which Pre-Vector is based, is on the target market of government interest for the fulfillment of health promises and international legislation that promote equal opportunities to medical access, likewise this market can be independent of the organizations, being (as an example the initial located market). Of the 21 states of the Mexican Republic in which vector-borne diseases (ETV) have been registered, the initial market segment will be limited to the population of around 14,500,000 people living in the 704 - out of a total of 1,154-- municipalities cataloged with extreme poverty and possible ailment of medical services in the states of Nayarit, Colima, Veracruz, Guerrero, Oaxaca, Chiapas, Tabasco, Campeche, Yucatan and Quintana Roo; where the main indigenous languages are concurrently spoken and there are ETV outbreaks with an incidence greater than 12.77 - that is, out of every 1,000 people, 127 will be prone to becoming ill - where the channels are: 1. Sales force. 2. Distributors. 3. Associated stores. The sales force and distributors will locate, and the latter will deliver the product to stores, pharmacies or associated social security centers. All this about the sale of diagnostic units, the wholesale of test strips and the sale of infrastructure to support the data management and analysis platform.

The wholesale price for the distributor will be MN $ 20,000.00 for the initial Package in modality of annual association contract. The suggested retail price for the self-service will be MN $ 30,000.00 in rental mode for the useful life - of 10 years in the unit of Pre-Vector, and 1-year on consumables. 

The recommended use is a Pre-Vector for community groups of up to 3,000 people that inhabit areas with ETV incidence equal to or greater than 10.0; thus the contribution of each user for the Acquisition of the initial package will be MN $ 10.00. against the MN $ 3,200.00 of the clinical diagnosis unfounded = $ 3,000.00 (3 clinical tests) + $ 100.00 (transfer) + $ 100.00 (food).