MIT Solve

Solution & Team Overview

Solution name:

Micro neural circuit transplantation-MNT

Short solution summary:

This surgical modality will benefit patients with paralysis, comatose patients and with neurodegenerative diseases. In recent pandemic we have seen people with these underlying disorders had increased mortality due to underlying conditions. Thus by this solution we will be reducing deaths in upcoming pandemics.

In what city, town, or region is your solution team based?

Bhubaneswar, Odisha, India

Who is the Team Lead for your solution?

Dr. Avinav Sahoo

Which Challenge Area does your solution most closely address?

Respond (Decrease transmission & spread), such as: Optimal preventive interventions & uptake maximization, Cutting through “infodemic” & enabling better response, Data-driven learnings for increased efficacy of interventions

What specific problem are you solving?

Problem within the challenge-

Covid-19 has been known to cause stroke in some patients. This surgical modality will help those people having stroke with paralysis or comatose patients. Patients with neurological deficits like paralysis and coma have a increased fatality rate considered to healthy persons in any pandemic.

Scale of problem within the community-

Globally there are 80 million people living with experienced stroke . Every year 5 million people either die of stroke or are permanently disabled. MNT will improve the quality of life those disabled people and people living with neurodegenerative diseases and reduce the amounts of death due to stroke or traumatic brain injury.

Factors leading to problem-

People in both developing country and developed country are having an unhealthy lifestyle.

There are genetic factors leading to neurodegenerative diseases and aging process which leads to both stroke and neurodegenerative diseases.

Traumatic brain injury can be due to accidents.

Statistics of problem-

In 2013, the Christopher & Dana Reeve Foundation unveiled staggering statistics based on research into the prevalence of paralysis across the U.S.

According to the study, there are nearly 1 in 50 people living with paralysis – approximately 5.4 million people. That's the same number of people as the combined populations of Los Angeles, Philadelphia, and Washington D.C. And that number is nearly 40 percent higher than previous estimates showed.

Who does your solution serve, and what needs of theirs does it address?

Target population-

People living with paralysis and coma, neurodegenerative diseases are target population.

This target population amounts to about 80 million.

The target population has a bad quality of life. This project seeks to improve the quality of life in the target population.

What is your solution’s stage of development?

Proof of Concept: A venture or organisation building and testing its prototype, research, product, service, or business/policy model, and has built preliminary evidence or data