Molecular Docking Startup Studio Course for Rare Disease

 Rare diseases may appear in the future, and possible molecular solutions would need to be discovered. The problem is a global problem. A rare disease is one that affects up to about 1 in 1,500 people. 

   Where a treatment is not known of, computer aided drug design (CADD) may be able to find solutions by means of computer simulations of possible chemical solutions. This is a factor contributing factor to the solution in that there is a certain probability that rare disease may a have treatment solution that is possibly able to be discovered from computer simulation of a finite set of candidate solutions.

  An online course for the creation of start up studios. The startup studios participants are given the computer tools for computer simulation of the dynamics of possible treatments by means of the molecular interaction with rare outcomes in genetics and even virology. 

 The business model for the project is envisioned to be to give the cures for rare diseases for free to those suffering from these diseases and to finance the project by means of the startup studio licensing the software and related technologies. The key market for the newly developed technologies will be for the treatment of diseases in general.

  The goal is to keep the program long running, which increases the likelihood of finding cures for a maximum possibly number of rare diseases by means of searching for molecular treatments from the existing database of molecular candidates.

WHAT IS MOLECULAR DOCKING?

 There now exists the ability to find molecules that can cure diseases by means of computer simulation. Molecular Docking is essentially the computer simulation of how a molecular cure would dock or bond to the target molecule in the patient and cure the disease. 

The approach to creating it, as mentioned in the first sentence, is by means of an online course that teaches how to develop the startup studio program.

   The solution also has a cultural benefit in that it encourages examining traditional and folk medicine in various cultures around the world from the perspective of the molecular level of what a certain herb may actually be doing to treat an ailment. It also gives startup studios a head start on what molecules to examine as possible treatment strategies to symptoms of some rare diseases.

The solution serves the following groups and impacts their lives in the following ways:

-The solution would aid this who suffer or may in the future suffer from rare diseases. 

-It also benefits the participants in the incubator in that they are able to develop the skills for a project that can help so many people. 

-The technology can be presented to local communities near the startup studio as applications of mathematics, chemistry, and physics for the potential discovery of cures for rare diseases by means of molecular docking. This could encourage the community, especially school-age children, to have a greater interest in these academic subjects.

-It encourages examining traditional and folk medicine in various cultures around the world from the perspective of the molecular level of what a certain herb may actually be doing to treat an ailment. It also gives startup studios a head start on what molecules to examine as possible treatment strategies to symptoms of some rare diseases.

The online course for the creation of startup studios for molecular docking has a component in the proposed application of the project in different communities as a modality of delivery the beneficial solution the these communities:

Many cultures have developed a tradition of herbal remedies, and the traditional medicine in their culture basically gives a startup studio a head start on what to look for in terms of how past cases rare disease in their community may have been treated at the molecular level. The solution, in this perspective, is guided by the communities' input and ideas.

Another example is education and what is the agenda in the community for education planning:

  The technology is envisioned to be  presented to local communities near the startup studio as applications of mathematics, chemistry, and physics for the potential discovery of cures for rare diseases by means of molecular docking. This could encourage the community, especially school-age children, to have a greater interest in these academic subjects.

The solution could help the many people who suffer now from rare diseases plus those in the future because the solution appears to be an approach that can work on finding new solutions over the years to come. 

OVERCOMING BARRIERS:

   Clearly, the first barrier is know versus unknown. The goal of the project is for the long term computer-based search for the molecular cures for rare diseases. The proposed project envisions overcoming financial barriers by means of the startup studio licensing software and related technologies that it will develop over time for the treatment of diseases in general by means of molecular docking. Some cultures may fear technology. However, many cultures have developed a tradition of herbal remedies, and the traditional medicine in their culture basically gives a startup studio a head start on what to look for in terms of how past cases rare disease in their community may have been treated at the molecular level.

It appears to be an innovative solution for finding cures for existing rare diseases as well as those that may arise in the future. It presents an online course to assist developers of computer aided drug design technology in the creation of startup studios. Along with this, it has an education resource function as well which is the following:

-The technology can be presented to local communities near the startup studio as applications of mathematics, chemistry, and physics for the potential discovery of cures for rare diseases by means of molecular docking. This could encourage the community, especially school-age children, to have a greater interest in these academic subjects.

FINANCING THE PROJECT AND MAXIMIZING THE ECONOMIC BENEFIT FOR THE TREATMENT OF RARE DISEASE:

An innovation the project envision is to give the cures discovered for free to those who suffer from rare disease. The project is envisioned to be financed primarily by means of licensing the software and related technologies with the main market being for the treatment of diseases in general.

The impact goal for the next year is for one cure for a rare disease to be discovered.

The impact goal for the next five years is for the strategic planning of multiple startup studios curing a multitude of rare diseases. 

These are the goals. It is not a guarantee that it will be accomplished, but a goal for the team, nonetheless.

The success rate of new medical discoveries from the molecular docking startup studios is how progress is primarily measured.

It works to create solutions for rare diseases in the future plus is an academic resource in that it creates applications for Fast Fourier transforms (FFT) and well as the Particle Swarm Optimization (PSO) family of algorithms. It provides the assistance of growth in the applications of existing technologies and provides the following change as well:

 Many cultures have developed a tradition of herbal remedies, and the traditional medicine in their culture basically gives a startup studio a head start on what to look for in terms of how past cases rare disease in their community may have been treated at the molecular level.

The core technologies are the various technologies for molecular docking as well as molecular docking itself.

  Examples of existing technologies applied to molecular docking include fast Fourier transforms(FFT),Simulated Annealing (SA), and Particle Swarm Optimization(PSO) algorithms.

The focus of the program is directly applied to encouraging diversity because the goal of the tech incubator is have as much diversity in national origin and race as a possible in order to address rare disease on the global scale.

  A key part of the diversity of the program is based on how folk medicine or traditional medicine from the Amazon rainforest to the steppes of Central Asia hold the theory of certain herbs curing ailments. This gives molecular docking a head start because it gives candidates for molecular cures to the symptoms of certain rare diseases. Cultural diversity, from this, is a key part of this proposed solution.

The primary goal is to finance the project by means of licensing the molecular docking technology that will be developed. In other words, the software and related technologies developed would be licensed as a source of revenue for maintaining the project. The main source of licensing revenue is envisioned to be for the applications to finding cures for diseases that affect the most number of people. With this, rare disease treatments discovered by the startup studios would be free to those in need.

  The primary goal is to finance the project over the long term by means of licensing revenue for new methodologies and software for molecular docking. The longer the project functions over time, the greater the probability of successfully finding cures for rare diseases.

   The secondary goal is to partially finance the online course and startup studios by means of philanthropic grants. With this, the project is envisioned to give the cures for rare diseases for free to those in need.

It has not achieved financial sustainability at this time.