Semi-finalist
Health in Fragile Contexts Challenge

Life Sign Network

Team Leader
José Trajano Feitosa Filho
Solution Overview & Team Lead Details
Our Organization
Life Sign Project
What is the name of your solution?
Life Sign Network
Provide a one-line summary of your solution.
We reduce the distance between patients and health systems with existing low-cost technologies in remote areas of the Amazon.
Film your elevator pitch.
What specific problem are you solving?

Our project focuses on solving a recurrent problem in one of Latin America’s most fragile regions: the reachability of some patients in the Amazon, where the high prevalence of cardiovascular diseases associated with specific geography, socioeconomic factors, and a river-based transport system—which results in days of travel between cities—creates a very particular and difficult situation. This arrangement creates an enormous gap between patients, who must be followed up, and the health teams that must follow them.

 

Cardiovascular diseases are a worldwide problem; hypertension alone affects 1.3 billion people currently. In 2020, the Brazilian Public Health System spent $2 billion in hospitalization and medicines on its 52,4 million hypertensive patients. In this delicate region, this scenario is even worse due to diet and cultural factors, such as the use of salt to keep protein fresh for longer in areas with no electrical power. In this area, where the prevalence of hypertensive men is around 28% and 23% for women, it reaches 67% in the elderly population.

 

In urban areas, only 40% of these hypertensive patients are currently under control, a number that is likely much worse in isolated areas due to a lack of appropriate diagnoses, treatment, and follow-up. In 2020, 29 million people live in the Brazilian Amazon, with 4 million of those in rural areas, where only 16% have access to the internet at home due to the high cost, difficult installation, and instability.

 

This population is remarkably arranged nearby and along the riverbanks during its course, using a sole river-based transportation system. This "liquid territory" changes seasonally and makes it even harder to travel during certain periods. Besides this, there is also electrical and connection isolation in the river course, which is only available near larger villages.

 

All these factors create a very complex situation, which results in inefficient, expensive, and laborious health assistance with several difficulties for capillarization. The teams, designated by the Ministry of Health and municipalities, spend weeks traveling by ship, going village by village, and trying to examine the largest possible number of patients at a time, since the next time they will return to that region again will be months later. This precious time is mostly used for resolving patient complaints and analyzing basic vital signs to adjust medications.

 

In emergency scenarios, people are transported thousands of kilometers to big cities with health infrastructure, sometimes taking more than 24 hours. Therefore, most patients do not get timely emergency care. For those who make it, there is an astronomical financial burden —totaling U$ 30.000,00 per person transported in a country with a minimum of U$ 236,00—and the patients are usually in critical condition due to this delay. Many patients die before reaching assistance.

 

All factors discussed above affect mortality rates. Research shows these populations have higher mortality rates than those in urban areas. This difference is colossal—sometimes 10 times more—when compared to developed countries. The government has historically tried to figure this problem out with no success.

What is your solution?

In order to solve this multiple-layer problem, our solution also has multiple layers of approaches and makes new use of some existing technologies in an innovative manner, reducing the gap between patients and the health system. To do so, we will work complementarily with local healthcare teams and systems, creating a more efficient way to provide continuous healthcare to this population.

 

Our strategy consists of providing families in this area with a diagnosis of cardiovascular disease with a kit that includes three inexpensive and existing sensors (glucometer, sphygmomanometer, and oximeter) at a total cost of $37,50. These sensors are synchronized with the mobile application installed on their cellphones, since most of these families have at least one smartphone to communicate when going to big villages.

 

This application is intuitive and developed with the illiterate in mind. It also contains educational content focused on healthy habits, diet (with optional healthy dishes of local cuisine), and avoidance of smoking or drinking to focus not only on the family member that already has a disease but also on lifestyle changes for all the patients, aiming for primary and secondary prevention care.

 

It allows families to monitor blood pressure and other parameters without having to annotate, remember, or get lost in the numbers because all the synchronization happens automatically. This data is saved on the patient’s phone and syncs automatically with our platform and become available to health teams responsible for that area. For those in no signal area, a small device (at a cost of $30,00) connects patients with our network.

 

This synchronization allows for continuous follow-up, evaluation of the effectiveness of treatment, and feedback using specific channels inside our app with the technology explained below.

 

For this continuous data exchange, our solution includes a low-cost long-range (LoRa) decentralized network, where every patient works as a bridge to connect the subsequent ones to the network. This long-range network arrangement allows data to be collected and send using multiple paths, chosen automatically, and provides a constant and robust low-data connection. The distance between these nodes can be as much as hundreds of kilometers, depending on the environment, making them excellent for our approach.

 

In addition to this robust and continuous but relatively slow connection, there is also a satellite link provided by StarLink antennas installed on the boats that already pass by these families daily, transporting cargo or people between cities. It creates a few minutes of high-speed connection every day that will be used for bigger data transfers, video-based telemedicine, and as a backup path to data synchronization with the health team.

 

As explained before, our goal is to optimize the already existing healthcare organization and infrastructure by reducing the well-known gap problem in our region. As an example, there are currently several telemedicine centers that provide healthcare to this population. However, they are very poorly utilized due to the connection problems and the physical distance, which requires several days of travel to reach these patients.

Who does your solution serve, and in what ways will the solution impact their lives?

Our solution serves the people living nearby and along the riverbank,  traditional populations, who only get checked up on their health every couple of months when the Primary Health Care Team approaches them to assist these populations in very specific demands and check their vital signs, sometimes making changes in medications, [based on a static view captured at that moment,] that cannot be tracked to see if they worked due to the fact that by the time another health team reaches them it will be months or years later.

The Life Sign project will impact their lives by filling the existing gap between these populations and the health care team. It also allows them to be able to check their glucose and blood pressure in an easy way through the kits distributed, and the information of those signs shared automatically with our app will be accessible to the health care team that already assists them, so any sort of concerning change in these signs will be assessed by the team so that necessary changes in medication or instructions to look for a healthcare facility will be transmitted to the patient via app.

Furthermore, our app will also contain educational videos about lifestyle habits to improve control of the disease and overall wellbeing that can be watched by the whole family. Our app will be intuitive and easy to use due to the lower level of education of most of these people. We will also partner with indigenous people who also speak Portuguese to offer our educational videos in the local indigenous languages, to increase accessibility.

 The healthcare team will be able to track any concerning signs and make the right changes in medication without having to wait many months before seeing the patient again, as well as tightening the contact between the health care team and patient, it will also serve as an educational platform that will actively aim to improve the control of the disease of those in the family with  existing conditions as well as improve the quality of life of those people. 

 Thus, it will serve as not only primary but also secondary prevention of health, which will be more cost effective for the Health System, saving thousands of dollars each year. When the system is in fully functional, the price that would fund one transportation in an emergency context ($30.000) will be able to track vital sings of 25.000 families per month. 

By having this robust approach, we will create a positive impact on these health professionals by optimizing their work for high-complexity tasks that are nowadays only done physically. It will also enable them to serve more areas at a timeand focus their attention to those who really need it, creating strategies specifically for them based on the collected information. In the end, superior health assistance will be provided to everyone at a lower cost, because of the focus on the prevention rather than on high-complexity emergence management in remote area. 

How are you and your team well-positioned to deliver this solution?

Our team is composed of people who live in the Amazon and are aware of the real conditions and complexities of this region, especially when it comes to health in fragile contexts. With a team of experts,composed of medical students, a cardiologist, a computer engineer, an obstetrician, and a marine engineer with experience in logistics, our team has the know-how necessary to tackle the healthcare knowledge and logistics needed in order to make these solutions work.

 The proximity of medical students from the Federal University of Amazonas with the reality of these isolated areas and services, such as the Telemedicine Center provided by the university hospital, is helping us integrate the proposed solution with the existing health infrastructure that is underutilized to make a greater impact with our project.

In favor of building the application interface, keeping in mind that it must be easy to use and intuitive, we have a computer engineer that already has vast experience developing apps and creating well thought product design. We are also working on a voice accessibility function so that illiterate people will be able to use it as well, not only in Portuguese but also in their native languages.

To make the educational videos for the platform, our team is charged with the most recent evidence about cardiovascular diseases to showcase the best ways to control existing diseases, as well as to have a healthy lifestyle. Our team has a large experience working with volunteer programs that have close contact with less affortunate populations, so we can create content that’s easy to understand while also sharing important information to this population. 

We have the main telehealth service in the region linked to our university and we are currently sharing experiences. The main developers of a big program that supports pregnant women in remote areas, an obstetrician, and a surgeon shared technical challenges, implementation process difficulties, and ways they communicate with authorities in these areas. Their know-how in this field is valuable to take into account so that our solution is well thought out and we face less difficulties in the implementation process by already foreseeing challenges and also planning the best way to get in touch with the authorities and population.    

To assess the dynamics of the local naval hub and the difficulties of inland navigation and peculiarities of waterway transport in the Amazon region, we have a marine engineer. Through the application of technical concepts and the norms of the maritime authority, the Brazilian Navy, the study has technical and normative support to be developed. Moreover, the engineer inserted in the local shipping market knows the peculiarities of intercity navigation, increasing the reliability of the study in relation to the dynamics of local navigation. In short, the presence of a naval engineer is essential to ensuring logistical feasibility and successful implementation in the region.

Our team still requires more people with experience in networks and technology of information, as well as business. We intend to find these people after funding. 

Which dimension of the Challenge does your solution most closely address?
  • Enable continuity of care, particularly around primary health, complex or chronic diseases, and mental health and well-being.
In what city, town, or region is your solution team headquartered?
Manaus
In what country is your solution team headquartered?
  • Brazil
What is your solution’s stage of development?
  • Prototype: A venture or organization building and testing its product, service, or business model, but which is not yet serving anyone
Please share details about what makes your solution a Prototype rather than a Concept.

Our solution consists of multiple steps to enhance the reachability and efficiency of healthcare by reducing the gap between patients and the healthcare system. Currently, these multiple steps have passed the stage of concept and are being tested, in different stages of maturity, in simulated and real-world conditions.

We understand that our approach is very audacious, and other attempts have failed in the past. Therefore, we decided to start with the hardest part and main barrier, which is the network infrastructure and hardware needed to surpass the physical distance and isolation inherent to our problem.

Presently, we already have a functioning network in Amazonas State that is independent of internet connections and the power grid. We achieve it by using a decentralized infrastructure in which every device (a radio with a LoRa protocol connection) is a hub to connect the others, creating a robust mesh connection. We also had extreme conditions in mind when we developed this system, which is entirely solar-powered and portable, in a region that changes seasonally and has one of the greatest solar irradiation indexes in the world. This allows for immediate use since it is preset to connect automatically to our network.

In order to simulate the environment of boats traveling by the river, we used our drones equipped with one of these small devices that transmit long-range signals that connect to multiple autonomous antennas (which are based on LoRa protocol and have Bluetooth to connect to the cellphone, like a WI-FI router, but instead of the internet, it connects to our long-range network) arranged in different locations in the city and outside it.

Our platform is also being developed as a prototype, with some basic functions already operating. It is being constantly modified to improve the user experience, reliability, and features. When it comes to the data migration from the sensors (glucometer, sphygmomanometer, and oximeter), we are currently working on ways to optimize this synchronization with our platform efficiently after being read by these instruments. Some manufacturers create barriers that make this migration difficult and demand some extra steps. So we are putting extra effort into this.

Working closely with the experts from the Federal University of Amazonas Telemedicine Center also facilitates our communication with different cities in our state to implement new features based on specific demands, such as using native language voice in our app to better interact with the indigenous population, which represents a significant percentage of the total in some cities. It is also creating a well-suited prototype that can be used more widely when we start our tests with a small number of patients with the help of the Telehealth Center.


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How many people does your solution currently serve?

Currently, we are in the prototype phase and have not reached the public yet. However, we are preparing for our pilot study, which will serve 75 families and expand to 150 in each of the 10 zones after the second year (reaching approximately 9000 people).

Why are you applying to Solve?

Historically, MIT Solve has given people real opportunities to innovate and create a better future in their context and globally.

 Being residents of one of the poorest regions in a developing country, such as Brazil, has always limited our attempts to create solutions to our real-life problems due to restrictions ranging from geographic isolation to economic limitations. Our team is composed mostly of experts with experience in our healthcare context who also appreciate technology and understand that its place in a digital world (especially with the fourth industrial revolution) can be the biggest instrument for equalizing health access in centuries.

By working in our hospitals, we can see how inequitable this health access can be. We can also feel the bad experiences and pain this population suffers during their journey searching for care. This difficulty is not limited to patients but also to the healthcare team, and a lot of these problems could be solved if we utilized technologies in better and more efficient ways, especially in healthcare. Sometimes spending 14 days of ship travel for an appointment that lasts 15 minutes and could be done remotely is a burden on the health system and also on patients time and quality of life.

Being nonconformist with the present arrangement and dynamics in health access and how they drive unequal and poor assistance, as in other areas, is a powerful tool that induces innovation and different ways of thinking in order to solve historical problems.

There is no better institution in the world that aggregates knowledge, principles, and a strong connection between the biggest centers of technology development. So, this is the reason why our team is trying to reach this network to help with our project implementation and consequently improve the lives of those who are invisible to most of the world.

We are sure that this arrangement of already existing technologies applied to solve this specific problem is a great approach that could also be modified to work in different environments that, for some reasons, have isolation, poverty, and difficult access as problems, like some regions in Latin America, the Middle East, Central Africa, and Southeast Asia. So, it is important to have the best directions, such as those provided by MIT’s experts and its network.

In which of the following areas do you most need partners or support?
  • Financial (e.g. accounting practices, pitching to investors)
  • Legal or Regulatory Matters
  • Technology (e.g. software or hardware, web development/design)
Who is the Team Lead for your solution?
José Trajano Feitosa Filho
More About Your Solution
Your Team
Your Business Model & Funding
Solution Team:
José Trajano Feitosa Filho
José Trajano Feitosa Filho
Janaína de Oliveira e Castro
Janaína de Oliveira e Castro
Carolina de Oliveira e Castro
Carolina de Oliveira e Castro
Lucas  Baltar
Lucas Baltar
Matheus  Carneiro
Matheus Carneiro