Submitted
2025 Global Health Challenge

MedBrain Global

Team Leader
Iñaki Alegria
MedBrain is a diagnostic copilot / diagnostic support system for healthcare professionals in low and middle-income nations. As a smart clinical assistant, it guides nurses and community health workers through the processes of delivering a structured clinical interview of the patient and family members, and a focused physical examination of the patient's body. MedBrain's questions are generated dynamically, based on...
What is the name of your organization?
MedBrain Global
What is the name of your solution?
MedBrain Global
Provide a one-line summary or tagline for your solution.
MedBrain is a clinical copilot providing reliable diagnostic support to healthcare professionals in low and middle-income nations.
In what city, town, or region is your solution team headquartered?
Addis Ababa, Ethiopia
In what country is your solution team headquartered?
ETH
What type of organization is your solution team?
Hybrid of for-profit and nonprofit
Film your elevator pitch.
What specific problem are you solving?
PROBLEM: ‘Half of the world’s population has no access to an accurate medical diagnosis’ - THE LANCET. - Source: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00673-5/fulltext - Population affected: 4 billion people. The most severe diagnostic gap exists in Sub-Saharan Africa, but is also significantly present in LMICs globally. Main Contributing Factors: The Global Diagnostic Gap is mostly caused by severe shortages in specialist doctors and in gold standard diagnostic tests. 1. Factor Nº1: Shortage in specialist doctors. - Representative data 1.1: ACCESS TO RADIOLOGISTS. High-income nations: 98/million population. Low-income nations: <2/million population. - Source 1.1: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(20)30751-8/abstract - Representative data 1.2: ACCESS TO PATHOLOGISTS. UK 46/million. Africa <1/million. - Source 1.2: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00673-5/fulltext 2. Factor Nº2: Shortage in diagnostic tests. - Representative data 2.1: ACCESS TO CLINICAL LABORATORIES. 37/49 African Nations have zero clinical laboratories accredited to basic quality standards (1988 USA CLIA and ISO 15189). - Source: 2.1: https://academic.oup.com/ajcp/article-abstract/141/6/791/1766526?redirectedFrom=fulltext&login=false - Representative data 2.2: ACCESS TO A CT SCANNER. High-income nations: >38/million population. Low-income nations: <0,7/million population. - Source: 2.2: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(20)30751-8/abstract
What is your solution?
MedBrain is a diagnostic copilot / diagnostic support system for healthcare professionals in low and middle-income nations. As a smart clinical assistant, it guides nurses and community health workers through the processes of delivering a structured clinical interview of the patient and family members, and a focused physical examination of the patient's body. MedBrain's questions are generated dynamically, based on the information gradually being inserted about the patient. After less than 15 dynamic questions, MedBrain provides an accurate Top 3 differential diagnosis together with a personalized step-by-step management plan, adapted to the resources available in each different clinical setting. MedBrain is delivered as a smartphone application that can work fully offline, with bidirectional synchronization (regular data backups) whenever users have connectivity. The Government of Nigeria has demonstrated that MedBrain allows allows primary care nurses and community health workers (CHWs) to diagnose their patients as accurately as a specialist doctor. This revolutionary value proposition ([Nurse or CHW + MedBrain = Specialist Physician] in terms of diagnostic & management accuracy) is backed by an independent, double-blind RCT (randomized controlled trial) and an observational trial, conducted by the Government of Nigeria and Government of Ethiopia, respectively.
Who does your solution serve, and in what ways will the solution impact their lives?
- Capacity Building Health Practitioners (primary care nurses, community health workers, and health extension workers): Health practitioners from the public primary care network, by becoming MedBrain certified, will receive capacity building in being able to lead a structured clinical interview and a focused physical examination, thus reaching an accurate clinical diagnosis and a correct management plan for each one of their patients. - Saving the Lives of Underserved Patients: Rural populations currently suffering from a diagnostic shortage stemming from a shortage in specialist physicians and a shortage in conventional diagnostic tests. With our new agreement with the Oromia Health Bureau (for deployment in 1.000 Primary Care centers), we will be impacting 64 million patients. MedBrain is a life saving solution. By providing early diagnosis and allowing for early management and early referral to a general hospital, we can substantially reduce mortality rates in rural communities of LMICs worldwide. - Optimizing the Government's Work Through Advanced Analytics: Federal Ministry of Health: The Government's health information team will receive advanced health analytics and will be able to optimize their public health policies, having a greater insight into the needs and problems of their citizenry and making better informed decisions because of it.
Solution Team:
Iñaki Alegria
Iñaki Alegria
Pediatrician
Pol Ricart
Pol Ricart